Research Article

Global Egr1-miRNAs Binding Analysis in PMA-Induced K562 Cells Using ChIP-Seq

Table 3

Enrichment of Gene Ontology molecular function terms in targets of miRNAs with EGR1 ChIP-Seq hits.

GO term IDsEnriched GO terms 𝑃 -value

GO:0005515Protein binding 2 . 9 3 𝐸 0 5
GO:0030528Transcription regulator activity 1 . 8 9 𝐸 0 4
GO:0051879Hsp90 protein binding 2 . 6 4 𝐸 0 4
GO:0003700Transcription factor activity 8 . 3 6 𝐸 0 4
GO:0004722Protein serine/threonine phosphatase activity 9 . 7 3 𝐸 0 4
GO:0004716Receptor signaling protein tyrosine kinase activity 1 . 5 3 𝐸 0 3
GO:0030618Transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity 1 . 6 2 𝐸 0 3
GO:0005488Binding 2 . 7 4 𝐸 0 3
GO:0003702RNA polymerase II transcription factor activity 3 . 3 8 𝐸 0 3
GO:0033613Transcription activator binding 6 . 0 8 𝐸 0 3
GO:0016563Transcription activator activity 7 . 2 2 𝐸 0 3
GO:0005072Transforming growth factor beta receptor, cytoplasmic mediator activity 8 . 4 4 𝐸 0 3
GO:0034713Type I transforming growth factor beta receptor binding 8 . 4 4 𝐸 0 3