BioMed Research International

Methodology Report

Identification of Multiple Hypoxia Signatures in Neuroblastoma Cell Lines by - Regularization and Data Reduction

Table 3

Hypoxia signatures generated after data filtering.


			Signatures
Probeset⁽¹⁾	Gene Name	GeneBank⁽²⁾	Apo⁽³⁾	Gly⁽³⁾	OxP⁽³⁾	All⁽³⁾

201848_s_at	BNIP3	U15174	100	—	—	100
201849_at	BNIP3	NM_004052	83	—	—	100
210512_s_at	VEGF	AF022375	78	—	—	100
211527_x_at	VEGF	M27281	61	—	—	—
212171_x_at	VEGF	H95344	61	—	—	—
219232_s_at	EGLN3	NM_022073	61	—	—	—
210513_s_at	VEGF	AF091352	56	—	—	—
221478_at	BNIP3L	AL132665	56	—	—	—
221479_s_at	BNIP3L	AF060922	56	—	—	—
222847_s_at	EGLN3	AI378406	56	—	—	—
202022_at	ALDOC	NM_005165	—	100	—	100
1558365_at	PGK1	AK055928	—	72	—	—
228483_s_at	PGK1	BE856250	—	72	—	—
208972_s_at	ATP5G1	AF100741	—	—	100	—
222270_at	SMEK2	BF509069	—	—	100	—
1554847_at	ATP6V1B1	AY039759	—	—	94	—
218201_at	NDUFB2	NM_004546	—	—	94	—
203189_s_at	NDUFS8	NM_005006	—	—	89	—
203371_s_at	NDUFB3	NM_002496	—	—	89	—
218200_s_at	NDUFB2	NM_013387	—	—	89	—
203606_at	NDUFS6	NM_002494	—	—	83	—
204125_at	NDUFAF1	NM_001687	—	—	83	—
214241_at	NDUFB8	BE043477	—	—	78	—
230598_at	KIAA1387	AI742966	—	—	78	—
203190_at	NDUFS8	NM_002496	—	—	72	—
207335_x_at	ATP5I	NM_006294	—	—	72	—
208745_at	ATP5L	AF092131	—	—	72	—
203039_s_at	NDUFS1	NM_021074	—	—	67	—
203613_s_at	NDUFB6	NM_004553	—	—	67	—
208746_x_at	ATP5L	AA917672	—	—	67	—
210453_x_at	ATP5L	U33833	—	—	67	—
211752_s_at	NDUFS7	AL050277	—	—	67	—
228816_at	ATP6AP1L	AU153583	—	—	67	—
207573_x_at	ATP5L	NM_005176	—	—	61	—
226616_s_at	NDUFV3	AW241758	—	—	61	—
200096_s_at	ATP6V0E	BC005876	—	—	56	—
214923_at	ATP6V1D	AV717561	—	—	56	—
226209_at	NDUFV3	BC006215	—	—	56	—
200078_s_at	ATP6V0B	BC035703	—	—	50	—
210206_s_at	DDX11	AF061735	—	—	50	—
213378_s_at	DDX11	AV711183	—	—	50	—
214244_s_at	ATP6V0E	AA723057	—	—	50	—
218190_s_at	UCRC	NM_004549	—	—	50	—
241755_at	UQCRC2	BE467348	—	—	50	—
243498_at	ATP5J	BG010493	—	—	50	—
202887_s_at	DDIT4	NM_019058	—	—	—	94
223193_x_at	E2IG5	AF201944	—	—	—	94
224345_x_at	E2IG5	AF107495	—	—	—	89
225342_at	AK3L1	AK026966	—	—	—	78
226452_at	PDK1	AU146532	—	—	—	78
236180_at	—	W57613	—	—	—	61
235850_at	WDR5B	BF434228	—	—	—	50

⁽¹⁾Probeset ID according to Affymetrix HG-U133 Plus 2.0 GeneChip. ⁽²⁾GenBank mRNA accession number. ⁽³⁾Frequency score as calculated by regularization for the selected probesets in the hypoxia signatures compared to the All-Chip signature. Apo: apoptosis; Gly: glycolisis; OxP: oxidative phosphorylation; All: All-chip.