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Journal of Biomedicine and Biotechnology
Volume 2010 (2010), Article ID 890674, 15 pages
Research Article

Detection of the Endosomal Sorting Complex Required for Transport in Entamoeba histolytica and Characterization of the EhVps4 Protein

1Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del IPN, México, CP 07360, Mexico
2Departamento de Modelos Experimentales de Enfermedades Humanas, Instituto de Investigaciones Biomédicas CSIC-UAM, Madrid, CP 28029, Spain
3Universidad Autónoma de la Ciudad de México, Posgrado en Ciencias Genómicas, México, CP 03100, Mexico
4Escuela Nacional de Medicina y Homeopatía del IPN, Programa Institucional de Biomedicina Molecular, México, CP 07320, Mexico

Received 23 September 2009; Revised 1 March 2010; Accepted 1 March 2010

Academic Editor: Abhay R. Satoskar

Copyright © 2010 Israel López-Reyes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Schematic representation of ESCRT machinery in E. histolytica, human and yeast. Most known domains described in homologous ESCRT proteins are depicted for E. histolytica factors. EhHse1, EhVps27, EhVps23, EhVps28, EhVps46 and EhRsp5 proteins that lack several consensus domains were considered as bona fide ESCRT components, since BLAST analysis showed that they share high identity with homologous human and yeast proteins (see Table 1). The scale is shown at the bottom.

  1. Supplementary Figure
  2. Supplementary Table