Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS
Figure 3
Protein mass spectra collected on CM10 and ProteinChip arrays with serum samples provided by five patients with arthritidies (including rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis) and five noninflammatory controls (NIC) (including osteoarthritis). (a) The inflammatory-related proteins S100A8, S100A12, S100A9, and one of its variant are arthritis biomarkers detected on CM10 arrays. (b) On ProteinChip arrays, SAA and its 2 variants (SAA-R and SAA-RS) are illustrated, reproduced from [19].