Characterization of Recombinant Dengue-2 Virus Derived from a Single Nucleotide Substitution in the 5′ Noncoding Region

Figure 4

Predicted RNA secondary (stems and loops) structure of 5^NCR of DEN2-16681 (stem1 = bases 3–9 and 64–71, stem2 = bases 11–16 and 56–61). The arrow represented the mutation position.

(a) DEN-2 16681

(b) D2-14.5^M

(c) D2-15.5^M

(d) D2-57.5^M