Research Article
Characterization of Recombinant Dengue-2 Virus Derived from a Single Nucleotide Substitution in the 5′ Noncoding Region
Table 3
Immunoprotection assay of DEN-2 mutants.
| PRNT titer against D2-16681 virus in pooled sera | Viruses | Immunized (day 5th) | Boost 1 (day 19th) | Boost 2 (day 33rd) | Challenged (day 38th) |
| D2-16681 | 160 | 640 | 1280 | 5120 | D2-14.M | 20 | 80 | 160 | 640 | D2-15.M | 80 | 160 | 160 | 1280 | D2-57.M | 40 | 160 | 320 | 2560 |
|
|