BioMed Research International / 2011 / Article / Fig 2

Review Article

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates

Figure 2

Regulation and functional ramifications of the HDAC6 deacetylase activity. Interaction with protein partners reduces protein deacetylase activity of HDAC6, which is important for the deacetylation of substrate proteins and cellular effects as indicated.