Research Article

Intermittent Chemotherapy and Erlotinib for Nonsmokers or Light Smokers with Advanced Adenocarcinoma of the Lung: A Phase II Clinical Trial

Table 1

Demographics, prognostic factors, and extent of disease.

No. of patients

Age
 Median50
 Range25–73

Gender
 Male12
 Female12

Smoking
 Never-smoker12
 Light smoker (<10 pack years)8

Performance status
 EGOG PS 05
 116
 23

Stage
 III B “wet”1
 IV23

Site(s) of metastatic disease
 Bone17
 Pleura and pericardium11
 Distant lung11
 Liver and/or suprarenals10
 Distant lymph nodes and/or soft tissues6
 Brain2

Number of metastatic sites
 18
 24
 3 or more12