Research Article
Intermittent Chemotherapy and Erlotinib for Nonsmokers or Light Smokers with Advanced Adenocarcinoma of the Lung: A Phase II Clinical Trial
Table 1
Demographics, prognostic factors, and extent of disease.
| | No. of patients |
| Age | | Median | 50 | Range | 25–73 |
| Gender | | Male | 12 | Female | 12 |
| Smoking | | Never-smoker | 12 | Light smoker (<10 pack years) | 8 |
| Performance status | | EGOG PS 0 | 5 | 1 | 16 | 2 | 3 |
| Stage | | III B “wet” | 1 | IV | 23 |
| Site(s) of metastatic disease | | Bone | 17 | Pleura and pericardium | 11 | Distant lung | 11 | Liver and/or suprarenals | 10 | Distant lymph nodes and/or soft tissues | 6 | Brain | 2 |
| Number of metastatic sites | | 1 | 8 | 2 | 4 | 3 or more | 12 |
|
|