|
| Models | Animal species | Treatment | Duration | Selected references |
|
| Carrageenan | Rats | 5%–10% degraded carrageenan in diet, drinking water or by stomach tube | 2, 6, 9 months or up to 24 months | Ashi et al., 1978 [89] Oohashi et al., 1981 [90] Ishioka et al., 1987 [91] Tobacman, 2001 [92] Benard et al., 2010 [93] |
|
| Dextran Sulfate Sodium (DSS) | C57Bl/6J | 0.1%–0.4% DSS | 60 days | Chromik et al., 2007 [94] |
| C57Bl/6J | 0.7% DSS | 15 cycles of: 1 week DSS followed by 10 days water | Kim et al., 2010 [95] |
| C57Bl/6J | 2.5% DSS | 12 cycles of: 7 days DSS followed by 10 days water | Seril et al., 2002 [96] |
| Mice | 3% DSS | 9 cycles of: 7 days DSS followed by 14 days water | Okayasu et al., 2002 [97] |
| C57Bl/6J | 4% DSS | 4 cycles of: 4 days DSS followed by 12 days water | Cooper et al. 2001 [98] |
| Wister Rats (Male) | 5% DSS | 5–8 cycles of: 4 days DSS followed by 10 days water | Kullmann et al., 2001 [99] |
| Swiss Webster mice | 5% DSS | 7 days DSS followed by 14 days water, sacrificed 120 days after the 4th cycle | Cooper et al. 2000 [100] |
|
| DSS & AOM | Mice (ICR,Balb/c, C57Bl/6J) | AOM (10 mg/kg of body weight) & 2% DSS in drinking water | Single IP AOM injection followed by 1 week 2% DSS | Tanaka et al., 2003 [101] Rosenberg et al., 2009 [102] Tanaka and Yasui, 2008 [103] |
|
| DSS & DMH | Mice (BALB/c) | 1 dose of DMH (20 mg/kg of body weight) & 3% DSS in drinking water | Single IP DMH injection followed by 3 cycles of 3% DSS | Kohno et al., 2005 [104] Tanaka et al., 2005 [105] |
|
| DSS & Iron | Mice (C57Bl/6J) | 2X Fe or 2X Fe-NAC diet & 0.7%–1% DSS | 12 or 15 cycles of DSS (1 DSS cycle = 7 days DSS followed by 10 days water) | Seril et al., 2002 [96]
Seril et al., 2002 [106]
Seril et al., 2003 [107]
Seril et al., 2006 [108] |
|
