Experimentally Approaching the ICU: Monitoring Outcome-Based Responses in the Two-Hit Mouse Model of Posttraumatic Sepsis

Figure 4

Retrospective comparison of neutrophil and lymphocyte count in dying (DIE) versus. surviving (SUR) animals prior to CLP. 3-month-old female mice were subjected to trauma/hemorrhage prior to CLP. Displayed values were compared between DIE and SUR at −48 h (DIE 𝑛=17, SUR 𝑛=18), −24 h (DIE 𝑛=29, SUR 𝑛=32) 0 h before-CLP (DIE 𝑛=31, SUR 𝑛=34) and between time points. Dots represent outlayers. ^§𝑃<.05 between time points.

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