Research Article

Effects of a Tumor Necrosis Factor-α Antagonist on Experimentally Induced Rhinosinusitis

Figure 4

Expression of MUC5AC mRNA in the rat nose on the 1st day after the last instillation of LPS. Expression of MUC5AC mRNA increased significantly in rats treated with LPS, and the upregulation of MUC5AC mRNA expression was inhibited by sTNFRI, antibiotic, and sTNFRI/antibiotic ( ).
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(a) Representative agarose gel showing the results of RT-PCR analysis for mRNA
360457.fig.004b
(b) Optical density ratio of MUC5AC mRNA as assessed by image analysis