Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription

<table>Schematic representation of human sirtuins family members 1–7, NAD-dependent catalytic domain (gold) (NAD-binding pocket), zinc-binding domain (black), and their intracellular localization.</table>

BioMed Research International

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Figure 1

Figure 1: Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription 