Table of Contents Author Guidelines Submit a Manuscript
Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 378268, 8 pages
http://dx.doi.org/10.1155/2011/378268
Research Article

Metabolomics Reveals Relationship between Plasma Inositols and Birth Weight: Possible Markers for Fetal Programming of Type 2 Diabetes

Department of Food Science, Faculty of Agricultural Sciences, Research Centre Aarslev, Aarhus University, Kirstinebjergvej 10, 5792 Aarslev, Denmark

Received 19 March 2010; Revised 20 April 2010; Accepted 3 June 2010

Academic Editor: Mika Ala-Korpela

Copyright © 2011 Pia Marlene Nissen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Forsdahl, “Living conditions in childhood and subsequent development of risk factors for arteriosclerotic heart. The cardiovascular survey in Finnmark 1974-75,” Journal of Epidemiology and Community Health, vol. 32, no. 1, pp. 34–37, 1978. View at Google Scholar · View at Scopus
  2. T. Harder, E. Rodekamp, K. Schellong, J. W. Dudenhausen, and A. Plagemann, “Birth weight and subsequent risk of type 2 diabetes: a meta-analysis,” American Journal of Epidemiology, vol. 165, no. 8, pp. 849–857, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. C. N. Hales and D. J. P. Barker, “Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis,” Diabetologia, vol. 35, no. 7, pp. 595–601, 1992. View at Publisher · View at Google Scholar · View at Scopus
  4. K. M. Godfrey and D. J. P. Barker, “Fetal nutrition and adult disease,” American Journal of Clinical Nutrition, vol. 71, no. 5, pp. 1344S–1352S, 2000. View at Google Scholar · View at Scopus
  5. L. Aerts and F. A. Van Assche, “Animal evidence for the transgenerational development of diabetes mellitus,” International Journal of Biochemistry and Cell Biology, vol. 38, no. 5-6, pp. 894–903, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. K. L. Kind, P. M. Clifton, and P. M. Clifton, “Effect of maternal feed restriction during pregnancy on glucose tolerance in the adult guinea pig,” American Journal of Physiology, vol. 284, no. 1, pp. R140–R152, 2003. View at Google Scholar · View at Scopus
  7. S. P. Burns, M. Desai, and M. Desai, “Gluconeogenesis, glucose handling, and structural changes in livers of the adult offspring of rats partially deprived of protein during pregnancy and lactation,” The Journal of Clinical Investigation, vol. 100, no. 7, pp. 1768–1774, 1997. View at Google Scholar · View at Scopus
  8. M. J. De Blasio, K. L. Gatford, I. C. McMillen, J. S. Robinson, and J. A. Owens, “Placental restriction of fetal growth increases insulin action, growth, and adiposity in the young lamb,” Endocrinology, vol. 148, no. 3, pp. 1350–1358, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. J. B. Susa, C. Neave, P. Sehgal, D. B. Singer, W. P. Zeller, and R. Schwartz, “Chronic hyperinsulinemia in the fetal rhesus monkey. Effects of physiologic hyperinsulinemia on fetal growth and composition,” Diabetes, vol. 33, no. 7, pp. 656–660, 1984. View at Google Scholar
  10. I. Cetin and G. Alvino, “Intrauterine growth restriction: implications for placental metabolism and transport. A review,” Placenta, vol. 30, pp. 77–82, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. A. L. Fowden and A. J. Forhead, “Endocrine mechanisms of intrauterine programming,” Reproduction, vol. 127, no. 5, pp. 515–526, 2004. View at Google Scholar · View at Scopus
  12. K. R. Poore and A. L. Fowden, “The effect of birth weight on glucose tolerance in pigs at 3 and 12 months of age,” Diabetologia, vol. 45, no. 9, pp. 1247–1254, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. J. J. Meier, “Linking the genetics of type 2 diabetes with low birth weight: a role for prenatal islet maldevelopment?” Diabetes, vol. 58, no. 6, pp. 1255–1256, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. R. M. Freathy, A. J. Bennett, and A. J. Bennett, “Type 2 diabetes risk alleles are associated with reduced size at birth,” Diabetes, vol. 58, no. 6, pp. 1428–1433, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  15. K. Zandi-Nejad, V. A. Luyckx, and B. M. Brenner, “Adult hypertension and kidney disease: the role of fetal programming,” Hypertension, vol. 47, no. 3, pp. 502–508, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. H. A. Martens and P. Dardenne, “Validation and verification of regression in small data sets,” Chemometrics and Intelligent Laboratory Systems, vol. 44, no. 1-2, pp. 99–121, 1998. View at Publisher · View at Google Scholar · View at Scopus
  17. H. Martens and M. Martens, “Modified Jack-knife estimation of parameter uncertainty in bilinear modelling by partial least squares regression (PLSR),” Food Quality and Preference, vol. 11, no. 1-2, pp. 5–16, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. S. E. Handel and N. C. Stickland, “Muscle cellularity and birth weight,” Animal Production, vol. 44, pp. 311–317, 1987. View at Google Scholar
  19. S. E. Powell and E. D. Aberle, “Skeletal muscle and adipose tissue cellularity in runt and normal birth weight swine,” Journal of Animal Science, vol. 52, no. 4, pp. 748–756, 1981. View at Google Scholar · View at Scopus
  20. P. V. J. Hegarty and C. E. Allen, “Effect of pre-natal runting on the post-natal development of skeletal muscles in swine and rats,” Journal of Animal Science, vol. 46, no. 6, pp. 1634–1640, 1978. View at Google Scholar · View at Scopus
  21. J. C. Lindon, J. K. Nicholson, and J. R. Everett, “NMR spectroscopy of biofluids,” Annual Reports NMR Spectroscopy, vol. 38, pp. 1–88, 1999. View at Google Scholar
  22. F. Gondret, L. Lefaucheur, H. Juin, I. Louveau, and B. Lebret, “Low birth weight is associated with enlarged muscle fiber area and impaired meat tenderness of the longissimus muscle in pigs,” Journal of Animal Science, vol. 84, no. 1, pp. 93–103, 2006. View at Google Scholar · View at Scopus
  23. N. Freinkel, “Banting Lecture 1980. Of pregnancy and progeny,” Diabetes, vol. 29, no. 12, pp. 1023–1035, 1980. View at Google Scholar
  24. M. Desai, N. J. Crowther, A. Lucas, and C. N. Hales, “Organ-selective growth in the offspring of protein-restricted mothers,” British Journal of Nutrition, vol. 76, no. 4, pp. 591–603, 1996. View at Publisher · View at Google Scholar
  25. C. B. Doherty, R. M. Lewis, A. Sharkey, and G. J. Burton, “Placental composition and surface area but not vascularization are altered by maternal protein restriction in the rat,” Placenta, vol. 24, no. 1, pp. 34–38, 2003. View at Publisher · View at Google Scholar
  26. K. L. Kind, J. A. Owens, and J. A. Owens, “Effect of restriction of placental growth on expression of IGFs in fetal sheep: relationship to fetal growth, circulating IGFs and binding proteins,” Journal of Endocrinology, vol. 146, no. 1, pp. 23–34, 1995. View at Google Scholar
  27. J. M. Kawa, R. Przybylski, and C. G. Taylor, “Urinary chiro-inositol and myo-inositol excretion is elevated in the diabetic db/db mouse and streptozotocin diabetic rat,” Experimental Biology and Medicine, vol. 228, no. 8, pp. 907–914, 2003. View at Google Scholar
  28. G. Sarashina, M. Yamakoshi, and M. Yamakoshi, “A study of urinary myo-inositol as a sensitive marker of glucose intolerance,” Clinica Chimica Acta, vol. 344, no. 1-2, pp. 181–188, 2004. View at Publisher · View at Google Scholar · View at PubMed
  29. T.-S. Jung, J.-R. Hahm, and J.-R. Hahm, “Determination of urinary myo-/chiro-inositol ratios from Korean diabetes patients,” Yonsei Medical Journal, vol. 46, no. 4, pp. 532–538, 2005. View at Google Scholar
  30. R. E. Ostlund Jr., J. B. McGill, I. Herskowitz, D. M. Kipnis, J. V. Santiago, and W. R. Sherman, “D-chiro-inositol metabolism in diabetes mellitus,” Proceedings of the National Academy of Sciences of the United States of America, vol. 90, no. 21, pp. 9988–9992, 1993. View at Publisher · View at Google Scholar
  31. I. Asplin, G. Galasko, and J. Larner, “Chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects,” Proceedings of the National Academy of Sciences of the United States of America, vol. 90, no. 13, pp. 5924–5928, 1993. View at Google Scholar
  32. K. P. Palmano, P. H. Whiting, and J. N. Hawthorne, “Free and lipid myo-inositol in tissues from rats with acute and less severe streptozotocin-induced diabetes,” Biochemical Journal, vol. 167, no. 1, pp. 229–235, 1977. View at Google Scholar
  33. J. Larner, “D-chiro-inositol-its functional role in insulin action and its deficit in insulin resistance,” International Journal of Experimental Diabetes Research, vol. 3, no. 1, pp. 47–60, 2002. View at Publisher · View at Google Scholar
  34. R. Bhandari, K. R. Juluri, A. C. Resnick, and S. H. Snyder, “Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 7, pp. 2349–2353, 2008. View at Publisher · View at Google Scholar · View at PubMed
  35. M. Thamotharan, B.-C. Shin, D. T. Suddirikku, S. Thamotharan, M. Garg, and S. U. Devaskar, “GLUT4 expression and subcellular localization in the intrauterine growth-restricted adult rat female offspring,” American Journal of Physiology, vol. 288, no. 5, pp. E935–E947, 2005. View at Publisher · View at Google Scholar · View at PubMed