Streptococcus thermophilus ST28 Ameliorates Colitis in Mice Partially by Suppression of Inflammatory Th17 Cells
Figure 4
Effects of S. thermophilus ST28 on percentages of Th17 (a) and inflammatory DC (b) in LPLs from DSS-induced colitis mice. (a) After the experiments described in Figure 3, LPLs from DSS-induced mice orally administered ST28 or ATCC 19258 were incubated with phorbol-12-myristate-13-acetate, ionomycin, and brefeldin A and applied to flow cytometry to measure intracellular IL-17. (b) Separately, flow cytometric analysis of surface marker CD86 was performed using freshly prepared LPLs. LPLs from untreated DSS-induced colitis mice (−) and healthy control mice (Cont) were also assayed. ND, not detected.
