Effects of Clofibrate on Salt Loading-Induced Hypertension in Rats

Table 1

Morphologic variables in the experimental groups.

Groups	Control	Clofibrate	Salt	Salt + clofibrate
FBW, g	381±9	368±7	325±5^∗	+284±4^∗
KW, g	1.19±0.03	1.22±0.03	1.26±0.06	1.33±0.02^∗
LVW, g	0.75±0.03	0.72±0.03	0.69±0.02	0.60±0.03^∗
KW/BW, mg/g	2.93±0.03	3.31±0.09^∗	3.92±0.24^∗	^++5.04±0.22^∗∗
LVW/BW, mg/g	1.98±0.06	1.98±0.05	2.13±0.11	2.30±0.11
LVW/RVW	3.71±0.41	4.24±0.52	4.66±0.79	3.44±0.55
LiW/BW, mg/g	29.97±0.75	37.52±1.01^∗	30.86±1.39	33.34±1.58
TW/BW, mg/g	1.82±0.07	2.05±0.14	1.60±0.09	1.69±0.06

Data expressed as means ± s.e.m. FBW, final body weight; KW, kidney weight; LVW, left ventricular weight; KW/BW, kidney weight versus body weight ratio; LVW/BW, left ventricular weight versus body weight ratio; LVW/RVW, left ventricular weight versus right ventricular weight ratio; LiW/BW, liver weight versus body weight ratio; TW/BW, thyroid weight versus body weight ratio. ^∗𝑃<.05, ^∗∗𝑃<.01 versus the control group; +𝑃<.05, ++𝑃<.01 versus the salt group.