Development of Novel In Silico Model to Predict Corneal Permeability for Congeneric Drugs: A QSPR Approach

Table 1

Structures of various fluoroquinolones used in the study.

Compound	X	R1	R5	R7
Norfloxacin	C	C2H5	H
Ciprofloxacin	C	c-C3H5	H
Lomefloxacin	C-F	C2H5	H
Ofloxacin	Fused C-1-8 (O) Cyclic ring		H
Levofloxacin	Fused C-1-8 (O) Cyclic ring		H
Sparfloxacin	C-F	c-C3H5	NH2
Pefloxacin	C	C2H5	H
Gatifloxacin	–C–OCH3	c-C3H5	H
Moxifloxacin	–C–OCH3	c-C3H5	H