Orange Juice and Its Component, Hesperidin, Decrease the Expression of Multidrug Resistance-Associated Protein 2 in Rat Small Intestine and Liver

Figure 4

Effect of hesperidin (Hes) on the plasma concentration of pravastatin (PRV) in Sprague-Dawley rats. A hesperidin suspension was prepared at a concentration of 79 mg per 100 mL of tap water (0.079%). The suspension instead of OJ was given according to the same schedule and volume as in the OJ study (Figure 1).