Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts
Figure 6
Analysis of cell cycle progression. Flow cytometric analysis of cell cycle progression in young, presenescent, and senescent HDFs (a). Quantitative analysis of cell cycle progression in untreated and TRF-treated HDFs at various stages of cellular ageing (b). Cell population in the S phase was lower in senescent HDFs. Treatment with TRF significantly increased cells in S phase and G2/M phase for all stages of cellular ageing of HDFs. In contrast, cell populations in G0/G1 phase decreased significantly with TRF treatment. aDenotes compared to S phase of untreated young HDFs, compared to untreated HDFs. Data are presented as mean ± SD, .
