A Novel Animal Model of Hippocampal Cognitive Deficits, Slow Neurodegeneration, and Neuroregeneration
Figure 5
Regardless of adrenalectomy (ADX), the combined enrichment and exercise treatment significantly increased neurogenesis as indexed by doublecortin (DCX). Representative pictures of DCX positive cells in the dentate gyrus of (a) home cage controls, (b) controls exposed to wheel running and enrichment, (c) ADX rats housed in the home cage, and (d) ADX rats exposed to wheel running and enrichment.
