Next-Generation Sequencing of MicroRNAs for Breast Cancer Detection

Table 1

Upregulated miRNAs (change >2 fold as a cutoff level) in cancerous tissue compared with noncancerous breast tissue.

miRNA	Reads in cancerous tissue	Reads in noncancerous tissue	Ration of cancerous and noncancerous tissue (normalized)
hsa-miR-29a	737	11	10.41
hsa-miR-23a	278	5	8.64
hsa-miR-192	452	9	7.80
hsa-miR-23b	200	5	6.21
hsa-miR-21	1228	37	5.15
hsa-miR-222	183	6	4.74
hsa-miR-761	264	9	4.55
hsa-miR-223	298	11	4.21
hsa-miR-1308	3347	132	3.94
hsa-miR-532-5p	138	6	3.57
hsa-miR-130b	370	20	2.87
hsa-miR-4315	301	17	2.75
hsa-miR-4308	86	5	2.67
hsa-miR-24	540	32	2.62
hsa-miR-125a-5p	79	5	2.45
hsa-miR-150	72	5	2.23
hsa-let-7f	222	16	2.15
hsa-let-7i	69	5	2.14
hsa-miR-103	1786	137	2.02