Research Article

Next-Generation Sequencing of MicroRNAs for Breast Cancer Detection

Table 3

The results of gene ontology analysis targets of differentially expressed miRNAs.

GO item, Targets of miR-29aTargets of miR-21

GO:0006350 transcription3623
GO:0006468 protein amino acid phosphorylation115
GO:0006810 transport113
GO:0006915 apoptosis81
GO:0007049 cell cycle97
GO:0007155 cell adhesion273
GO:0007156 homophilic cell adhesion141
GO:0007165 signal transduction1914
GO:0007242 intracellular signaling cascade22
GO:0007267 cell-cell signaling23
GO:0007275 development2210
GO:0008152 metabolism34
GO:0008283 cell proliferation23
GO:0008380 RNA splicing33
GO:0016568 chromatin modification65
GO:0030154 cell differentiation115

Values expressed as the number of genes targeted by miRNA.