Synergistic Effects between Phosphorylation of Phospholamban and Troponin I Promote Relaxation at Higher Heart Rate
Figure 1
Cardiac output of isolated working hearts in the pacing and ISO treatment. All data are mean ± SEM. (a) Cardiac output of isolated working hearts in different rates of pacing. The hearts. * versus baseline. (b) Cardiac output in different concentrations of ISO treatment. The hearts in each ISO concentration. * or ** versus baseline. (c) The percentage increases in cardiac output in the heart rate increment of 60 beats/min. The hearts for each group. * versus the pacing group. (d) The percentage increases in cardiac output at the pacing of 420 beats/min without and with ISO treatment. The hearts in each ISO concentration. * or ** versus baseline.