BioMed Research International / 2011 / Article / Tab 1

Research Article

Synergistic Antitumor Effect of Dichloroacetate in Combination with 5-Fluorouracil in Colorectal Cancer

Table 1

values (concentrations required to reduce the viability of cells by 50% as compared with the control cells) were computed using linear or nonlinear regression (three parametric Hill function) ( ). They are presented as mean ± SD from at least three independent experiments. IC50 values of the studied drugs for inhibition of growth of various cell lines (cells were incubated with drugs for 48 hours).

DrugsIC50
SW620LoVoLS174tHT29

5-FU ( M)
DCA (mM)

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