BioMed Research International / 2011 / Article / Tab 2

Research Article

Synergistic Antitumor Effect of Dichloroacetate in Combination with 5-Fluorouracil in Colorectal Cancer

Table 2

SW620, LoVo, LS174t, HT29 cells, and 293T noncancerous controls were treated with 10 mM DCA and 20 μM 5-FU alone or in combination for 48 hours, and then pulsed with BrdU. Cells were then harvested and stained, and the numbers of BrdU+ cells were calculated as the mean number of the positive cells in eight different fields of view in one image (magnification, 400X). This calculation was repeated three times. * , compared with control. BrdU+  cells in different drug treatment (%, mean ± SD).

DrugsBrdU+  rate
SW620LoVoLS174tHT29

untreated
5-FU
DCA
5-FU+DCA

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