Research Article

Neuroprotective Effect of Phosphocreatine on Focal Cerebral Ischemia-Reperfusion Injury

Table 1

Neurologic score after 24 and 72 h of ischemia after middle cerebral artery occlusion.

GroupNeurological score
24 h72 h

IR group 7 . 3 1 ± 2 . 0 3 5 . 6 3 ± 1 . 4 1
P1 group 6 . 3 6 ± 1 . 3 6 4 . 8 4 ± 1 . 6 2
P2 group 5 . 1 1 ± 1 . 2 2 *,† 2 . 6 1 ± 1 . 6 3 *,†
P3 group 4 . 9 5 ± 1 . 4 3 *,†,‡ 1 . 9 5 ± 1 . 1 6 *,†

𝑃 < 0 . 0 1 , versus IR group. There were significant differences of neurological score in P1, P2, P3 groups than that in IR group; 𝑃 < 0 . 0 5 , versus P1 group. There were significant differences of neurological score in P2, P3 groups than that in P1 group; v e r s u s P2 group. There were significant differences of neurological score between P2 and P3 groups. But in 72 h, there was no significant difference of neurological score between P2 and P3 groups.