Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid

Figure 2

Cell lines (LNCaP, C4-2) were treated with 0, 0.6, and 1.2 mM of VPA for 14 days. TMA were created from cell pellets followed by IHC staining for expression of markers. Representative images of p21, p27, CK18, AR, and Ki-67 staining are shown (scanned at 20x magnification using the APERIO imaging system).