|
| Official gene symbol |
Gene name | Entrez gene ID | Ensembl genomic location |
|
| Apical junctional complex | CDH1 | Cadherin 1, type 1, E-cadherin (epithelial) | 999 | 16q22.1 |
| CDH2 | Cadherin 2, type 1, N-cadherin (neuronal) | 1000 | 18q12.1 |
| CLDN1 | Claudin 1 | 9076 | 3q28 |
| CLDN2 | Claudin 2 | 9075 | Xq22.3 |
| CLDN3 | Claudin 3 | 1365 | 7q11.23 |
| CLDN4 | Claudin 4 | 1364 | 7q11.23 |
| CLDN5 | Claudin 5 | 7122 | 22q11.21 |
| CLDN6 | Claudin 6 | 9074 | 16p13.3 |
| CLDN7 | Claudin 7 | 1366 | 17p13.1 |
| CLDN8 | Claudin 8 | 9073 | 21q22.11 |
| CLDN9 | Claudin 9 | 9080 | 16p13.3 |
| CLDN10 | Claudin 10 | 9071 | 13q32.1 |
| CLDN11 | Claudin 11 | 5010 | 3q26.2 |
| CLDN12 | Claudin 12 | 9069 | 7q21.13 |
| CLDN14 | Claudin 14 | 23562 | 21q22.3 |
| CLDN15 | Claudin 15 | 24146 | 7q22.1 |
| CLDN16 | Claudin 16 | 10686 | 3q28 |
| CLDN17 | Claudin 17 | 26285 | 21q22.11 |
| CLDN18 | Claudin 18 | 51208 | 3q22.3 |
| CLDN23 | Claudin 23 | 137075 | 8p23.1 |
| CTNNA1 | Catenin (cadherin-associated protein), alpha 1 | 1495 | 5q31.2 |
| CTNNB1 | Catenin (cadherin-associated protein), beta 1 | 1499 | 3p22.1 |
| CTNND1 | Catenin (cadherin-associated protein), delta 1 | 1500 | 11q12.1 |
| JAM2 | Junctional adhesion molecule 2 | 58494 | 21q21.3 |
| JAM3 | Junctional adhesion molecule 3 | 83700 | 11q25 |
| JUP | Junction plakoglobin | 3728 | 17q21.2 |
| MAGI1 | Membrane associated guanylate kinase, WW and PDZ domain containing 1 | 9223 | 3p14.1 |
| MARVELD2 | MARVEL domain containing 2 | 153562 | 5q13.2 |
| OCLN | Occludin | 4950 | 5q13.2 |
| PVRL1 | Poliovirus receptor-related 1 (herpesvirus entry mediator C) | 5818 | 11q23.3 |
| PVRL2 | Poliovirus receptor-related 2 (herpesvirus entry mediator B) | 5819 | 19q13.32 |
| PVRL3 | Poliovirus receptor-related 3 | 25945 | 3q13.13 |
| PVRL4 | Poliovirus receptor-related 4 | 81607 | 1q23.3 |
| SYMPK | Symplekin | 8189 | 19q13.32 |
| TJP1 | Tight junction protein 1 (zona occludens 1) | 7082 | 15q13.1 |
| TJP2 | Tight junction protein 2 (zona occludens 2) | 9414 | 9q21.11 |
| TJP3 | Tight junction protein 3 (zona occludens 3) | 27134 | 19p13.3 |
| VCL | Vinculin | 7414 | 10q22.2 |
|
| Apoptosis | BAX | BCL2-associated X protein | 581 | 19q13.33 |
| BCL2 | B-cell CLL/lymphoma 2 | 596 | 18q21.33 |
| CASP2 | Caspase 2, apoptosis-related cysteine peptidase | 835 | 7q34 |
| ERBB2 | V-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (avian) | 2064 | 17q12 |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 4193 | 12q15 |
| TP53 | Tumor protein p53 | 7157 | 17p13.1 |
| TP53INP1 | Tumor protein p53 inducible nuclear protein 1 | 94241 | 8q22.1 |
| XIAP | X-linked inhibitor of apoptosis | 331 | Xq25 |
|
| Basal markers | ACTA1 | Actin, alpha 1, skeletal muscle | 58 | 1q42.13 |
| CD44 | CD44 molecule (Indian blood group) | 960 | 11p13 |
| EGFR | Epidermal growth factor receptor | 1956 | 7p11.2 |
| KRT5 | Keratin 5 | 3852 | 12q13.13 |
| KRT6A | Keratin 6A | 3853 | 12q13.13 |
| KRT6B | Keratin 6B | 3854 | 12q13.13 |
| KRT14 | Keratin 14 | 3861 | 17q21.2 |
| KRT17 | Keratin 17 | 3872 | 17q21.2 |
| TP63 | Tumor protein p63 | 8626 | 3q28 |
| VIM | Vimentin | 7431 | 10p13 |
|
| Cell cycle | CCNB3 | Cyclin B3 | 85417 | Xp11.22 |
| CCND1 | Cyclin D1 | 595 | 11q13.3 |
| CCNE2 | Cyclin E2 | 9134 | 8q22.1 |
| CDK2 | Cyclin-dependent kinase 2 | 1017 | 12q13.2 |
| CDK4 | Cyclin-dependent kinase 4 | 1019 | 12q14.1 |
| CDK6 | Cyclin-dependent kinase 6 | 1021 | 7q21.2 |
| CDKN1A | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 1026 | 6p21.2 |
| CDKN1B | Cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 1027 | 12p13.1 |
| CDKN2A | Cyclin-dependent kinase inhibitor 2A (melanoma, p16, CDK4) | 1029 | 9p21.3 |
| CDKN2B | Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 1030 | 9p21.3 |
| CDKN2D | Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 1032 | 19p13.2 |
| GAS1 | Growth arrest-specific 1 | 2619 | 9q21.33 |
| MKI67 | Antigen identified by monoclonal antibody Ki-67 | 4288 | 10q26.2 |
|
| Cell polarity complexes | CRB1 | Crumbs homolog 1(Drosophila) | 23418 | 1q31.3 |
| CRB3 | Crumbs homolog 3 (Drosophila) | 92359 | 19p13.3 |
| DLG1 | Discs, large homolog 1 (Drosophila) | 1739 | 3q29 |
| DLG2 | Discs, large homolog 2 (Drosophila) | 1740 | 11q14.1 |
| DLG3 | Discs, large homolog 3 (Drosophila) | 1741 | Xq13.1 |
| DLG4 | Discs, large homolog 4 (Drosophila) | 1742 | 17p13.1 |
| DLG5 | Discs, large homolog 5 (Drosophila) | 9231 | 10q22.3 |
| INADL | InaD-like (Drosophila) | 10207 | 1p31.3 |
| MPP5 | Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | 64398 | 14q23.3 |
| LLGL1 | Lethal giant larvae homolog 1 (Drosophila) | 3996 | 17p11.2 |
| LLGL2 | Lethal giant larvae homolog 2 (Drosophila) | 3993 | 17q25.1 |
| PARD3 | Par-3 partitioning defective 3 homolog (C. elegans) | 56288 | 10p11.21 |
| PARD3B | Par-3 partitioning defective 3 homolog B (C. elegans) | 117583 | 2q33.3 |
| PARD6A | Par-6 partitioning defective 6 homolog alpha (C. elegans) | 50855 | 16q22.1 |
| PARD6B | Par-6 partitioning defective 6 homolog beta (C. elegans) | 84612 | 20q13.13 |
| PARD6G | Par-6 partitioning defective 6 homolog gamma (C. elegans) | 84552 | 18q23 |
| PRKCI | Protein kinase C, iota | 5584 | 3q26.2 |
| PRKCZ | Protein kinase C, zeta | 5590 | 1p36.33 |
| SCRIB | Scribbled homolog (Drosophila) | 23513 | 8q24.3 |
|
|
Epithelial-mesenchymal transition | AKT1 | V-akt murine thymoma viral oncogene homolog 1 | 207 | 14q32.33 |
| AKT2 | V-akt murine thymoma viral oncogene homolog 2 | 208 | 19q13.2 |
| BMP1 | Bone morphogenetic protein 1 | 649 | 8p21.3 |
| ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 3397 | 20q11.21 |
| ID2 | Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3398 | 2p25.1 |
| ID3 | Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3399 | 1p36.12 |
| ID4 | Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 3400 | 6p22.3 |
| SMAD2 | SMAD family member 2 | 4087 | 18q21.1 |
| SMAD3 | SMAD family member 3 | 4088 | 15q22.33 |
| SMAD4 | SMAD family member 4 | 4089 | 18q21.2 |
| SMAD5 | SMAD family member 5 | 4090 | 5q31.1 |
| SMAD6 | SMAD family member 6 | 4091 | 15q22.31 |
| SMAD7 | SMAD family member 7 | 4092 | 18q21.1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 57154 | 7q22.1 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 64750 | 17q24.1 |
| SNAI1 | Snail homolog 1 (Drosophila) | 6615 | 20q13.13 |
| SNAI2 | Snail homolog 2 (Drosophila) | 6591 | 8q11.21 |
| TCF3 | Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 6929 | 19p13.3 |
| TGFBI | Transforming growth factor, beta-induced, 68 kDa | 7045 | 5q31.1 |
| TGFBR1 | Transforming growth factor, beta receptor 1 | 7046 | 9q22.33 |
| TGFBR2 | Transforming growth factor, beta receptor II | 7048 | 3p24.1 |
| TGFBR3 | Transforming growth factor, beta receptor III | 7049 | 1p22.1 |
| TGIF2 | TGFB-induced factor homeobox 2 | 60436 | 20q11.23 |
| TWIST1 | Twist homolog 1 (Drosophila) | 7291 | 7p21.1 |
| TWIST2 | Twist homolog 2 (Drosophila) | 117581 | 2q37.3 |
| ZEB1 | Zinc finger E-box binding homeobox 1 | 6935 | 10p11.22 |
| ZEB2 | Zinc finger E-box binding homeobox 2 | 9839 | 2q22.3 |
|
| Luminal markers | CD24 | CD24 molecule | 100133941 | 6q21 |
| ESR1 | Estrogen receptor 1 | 2099 | 6q25.1 |
| GATA3 | GATA binding protein 3 | 2625 | 10p14 |
| KRT7 | Keratin 7 | 3855 | 12q13.13 |
| KRT8 | Keratin 8 | 3856 | 12q13.13 |
| KRT18 | Keratin 18 | 3875 | 12q13.13 |
| KRT19 | Keratin 19 | 3880 | 17q21.2 |
| MUC1 | Mucin 1, cell surface associated | 4582 | 1q22 |
| PGR | Progesterone receptor | 5241 | 11q22.1 |
|
| Metastasis-related genes | CXCR4 | Chemokine (C-X-C motif) receptor 4 | 7852 | 2q22.1 |
| CXCR5 | Chemokine (C-X-C motif) receptor 5 | 643 | 11q23.3 |
| MMP1 | Matrix metallopeptidase 1 (interstitial collagenase) | 4312 | 11q22.2 |
| MMP2 | Matrix metallopeptidase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) | 4313 | 16q12.2 |
| MMP3 | Matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 4314 | 11q22.2 |
| MTA1 | Metastasis associated 1 | 9112 | 14q32.33 |
| MTA2 | Metastasis associated 1 family, member 2 | 9219 | 11q12.3 |
| MTA3 | Metastasis associated 1 family, member 3 | 57504 | 2p21 |
| PAK6 | P21 protein (Cdc42/Rac)-activated kinase 6 | 56924 | 15q15.1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 7076 | Xp11.23 |
|
| Stemlike features | ABCG2 | ATP-binding cassette, sub-family G (WHITE),member 2 | 9429 | 4q22.1 |
| ALDH1A1 | Aldehyde dehydrogenase 1 family, member A1 | 216 | 9q21.13 |
| ALDH1A3 | Aldehyde dehydrogenase 1 family, member A3 | 220 | 15q26.3 |
| BMI1 | BMI1 polycomb ring finger oncogene | 648 | 10p12.2 |
| JAG1 | Jagged 1 | 182 | 20p12.2 |
| JAG2 | Jagged 2 | 3714 | 14q32.33 |
| NANOG | Nanog homeobox | 79923 | 12p13.31 |
| NOTCH1 | Notch 1 | 4851 | 9q34.3 |
| NOTCH2 | Notch homolog 2 (Drosophila) | 4853 | 1p12 |
| NOTCH3 | Notch homolog 3 (Drosophila) | 4854 | 19p13.12 |
| NOTCH4 | Notch homolog 4 (Drosophila) | 4855 | 6p21.32 |
| NUMB | Numb homolg (Drosophila) | 8650 | 14q24.3 |
| PROM1 | Prominin 1 | 8842 | 4p15.32 |
|
