BioMed Research International / 2012 / Article / Fig 4

Research Article

Exposure to Low Dose of Cinnabar (a Naturally Occurring Mercuric Sulfide (HgS)) Caused Neurotoxicological Effects in Offspring Mice

Figure 4

Changes in locomotor activities and motor equilibrium performance of offspring mice treated with cinnabar. Experimental mice were treated with cinnabar (10 mg/kg/day) or distilled water as described in Figure 1. Spontaneous locomotor activities (ambulatory distance (a), stereotypy-1 episodes (b) and Jump (c)) and motor equilibrium performance (retention times on rotating rod, 60 rpm (d)) of all groups were recorded and analyzed as described of Materials and Methods. Data are presented as mean ± SE ( 𝑛 = 12–15/group). * 𝑃 < 0 . 0 5 as compared with F1-C-V group; & 𝑃 < 0 . 0 5 as compared with F1- or F2-Cin-V group; # 𝑃 < 0 . 0 5 as compared with F1-C-Cin group, respectively.

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