Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders

<table>Dopamine transporter (DAT) imaging with <sup>99m</sup>Tc-TRODAT-1 and dopamine D<sub>2</sub> receptor imaging with<sup> 123</sup>I-IBZM of healthy volunteer and patients with Parkinson’s disease (PD), multiple-system atrophy (MSA), and progressive supranuclear palsy (PSP). The striatal DAT uptakes were significantly decreased in patients with PD, MSA, and PSP, whereas the dopamine D<sub>2</sub> receptor uptakes were mildly decreased in patients with PD, MSA, and PSP.</table>

BioMed Research International

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Figure 2: Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders 