All-trans-Retinoic Acid Ameliorated High Fat Diet-Induced Atherosclerosis in Rabbits by Inhibiting Platelet Activation and Inflammation
Figure 2
Platelet fibrinogen binding in different groups. Platelets isolated from rabbits were incubated with FITC-labelled anti-fibrinogen antibody and analyzed with flow cytometry to examine the platelets surface change. Representative histograms are shown. (a) The binding of fibrinogen on the resting platelets surface from different groups. (b) The binding of fibrinogen on the thrombin-activated platelets from different groups. (c) The binding of fibrinogen on the ADP-activated platelets from different groups. (d) Mean fluorescence intensity (MFI) of fibrinogen binding on platelets surface in different groups. Data are mean ± standard deviation (SD). Comparisons between groups were carried out using one-way analysis of variance (ANOVA) and Student-Newman-Keuls (SNK) method (). ** compared to control group, ▲, ▲▲ compared to HFD group.
