Table 1: Values of CC50 and EC50 of baicalin, baicalein, wogonoside, and wogonin.

CompoundsCC50 EC50 SI
μg/mL (mmol/L)μg/mL (mmol/L)

Baicalin188.4 (0.422)1.2 (0.0027)156
Wogonoside13.7 (0.0298)7.4 (0.0161)1.85
Baicalein8.9 (0.0329)1.0 (0.0037)8.89
Wogonin10.6 (0.0373)4.3 (0.0151)2.47

CC50 means the 50% cytotoxic concentration.
EC50 means the 50% effective concentration.
SI (the safety index) was calculated by CC50/EC50.