TY - JOUR A2 - Miles, Lindsey A. AU - Sanderson-Smith, Martina L. AU - De Oliveira, David M. P. AU - Ranson, Marie AU - McArthur, Jason D. PY - 2012 DA - 2012/10/14 TI - Bacterial Plasminogen Receptors: Mediators of a Multifaceted Relationship SP - 272148 VL - 2012 AB - Multiple species of bacteria are able to sequester the host zymogen plasminogen to the cell surface. Once localised to the bacterial surface, plasminogen can act as a cofactor in adhesion, or, following activation to plasmin, provide a source of potent proteolytic activity. Numerous bacterial plasminogen receptors have been identified, and the mechanisms by which they interact with plasminogen are diverse. Here we provide an overview of bacterial plasminogen receptors and discuss the diverse role bacterial plasminogen acquisition plays in the relationship between bacteria and the host. SN - 2314-6133 UR - https://doi.org/10.1155/2012/272148 DO - 10.1155/2012/272148 JF - Journal of Biomedicine and Biotechnology PB - Hindawi Publishing Corporation KW - ER -