BioMed Research International

Research Article

Sleep Deprivation Alters Rat Ventral Prostate Morphology, Leading to Glandular Atrophy: A Microscopic Study Contrasted with the Hormonal Assays

Table 1

ControlPSD96 hSR21
Morphometry   
Epithelium height (μm) 4 3 . 4 2 ± 7 . 3 3 8 . 7 ± 5 . 4 ∗ 3 8 . 5 ± 5 . 2 ∗
Estereology   
Epithelium   
 RV (%) 3 3 . 8 4 ± 2 . 3 3 3 1 . 6 ± 7 . 2 2 9 . 1 ± 7
 AV (mg) 3 5 . 4 3 ± 2 . 4 4 2 5 . 8 8 ± 1 . 7 1 ∗ 2 2 . 5 2 ± 1 . 0 8 ∗
Stroma   
 RV (%) 1 0 . 7 ± 0 . 6 7 1 2 . 2 ± 6 ∗ 2 0 . 2 ± 8 . 7 ∗ #
 AV(mg) 1 1 . 1 7 ± 0 . 6 7 1 0 . 0 2 ± 0 . 9 7 1 5 . 6 5 ± 1 . 3 5 ∗ #
Lumen   
 RV (%) 5 5 . 5 ± 1 3 . 3 5 6 . 2 ± 1 0 5 0 . 8 ± 9 ∗ #
 AV (mg) 5 8 . 0 7 ± 2 . 7 9 4 5 . 9 9 ± 1 . 6 3 ∗ 3 9 . 3 6 ± 1 . 4 0 ∗
Values represent means ± SEMs of the data obtained for stereological and morphometrical analyses of three experimental groups: control, PSD96 h and SR21. Statistical analyses based on ANOVA and Tukey tests. Significance 𝑃 < 0 . 0 5 . *Different from control group and different from PSD96 h. RV: relative volume. AV: absolute volume.