A Standardized Extract of Ginkgo biloba Neutralizes Cisplatin-Mediated Reproductive Toxicity in Rats

Figure 2

Photomicrograph of cross-sections of the testes of control (N), GB alone (GB), CIS alone (CIS), and the three GB-protected rats (CIS+L: 50 mg/kg GB; CIS+M: 100 mg/kg GB; CIS+H: 200 mg/kg GB). Testes of control and GB alone treated groups show normal arrangement of germ cells and Sertoli cells. However, CIS-treated testes show extensive atrophy of seminiferous tubules and degenerations of germ cells. Rats protected with different GB doses clearly show less degeneration of some tubules and irregular derangement of some germ cells (H & E 400x).