Research Article

Evaluation of DNA Single and Double Strand Breaks in Women with Cervical Neoplasia Based on Alkaline and Neutral Comet Assay Techniques

Table 1

DNA damage evaluated in alkaline conditions (ssb + dsb) and in neutral conditions (dsb) in women with LG-SIL and HG-SIL and in control women.

Mean comet percentage ± SD (Range)
ControlLG-SIL HG-SIL

Global (ssb + dsb) 2 1 . 7 0 ± 1 1 . 8 9 (8–46) 3 3 . 6 0 ± 1 4 . 9 6 (9–64) 4 8 . 9 0 ± 1 2 . 8 7 (34–72)*
dsb 5 . 3 0 ± 5 . 3 8 (1–16) 1 1 . 2 0 ± 5 . 7 1 (2–20) 2 3 . 5 0 ± 1 3 . 9 1 (5–49)*

* ANOVA; Different to control 𝑃 < 0 . 0 5 .