Metabolomics Analysis of Cistus monspeliensis Leaf Extract on Energy Metabolism Activation in Human Intestinal Cells

Table 2

Effect of C. monspeliensis extract on the metabolomics by Caco-2 cells. Quantified levels of metabolites involved in glycolysis pathway were determined. Caco-2 cells were treated with 0.1% (w/v) C. monspeliensis extract for 12 h. The ratio of quantified levels of metabolites was calculated by Caco-2 cells treated or nontreated with C. monspeliensis extract.

Metabolite	Ratio
Glycolysis
Glucose 6-phosphate	1.7
Fructose 6-phosphate	1.6
Fructose 1,6-diphosphate	1.5
Dihydroxyacetone phosphate	2.1
3-Phosphoglyceric acid	1.0
Phosphoenolpyruvic acid	0.8
Pyruvic acid	4.2
TCA cycle
Acetyl CoA_divalent	0.7
Citric acid	1.5
Cis-aconitic acid	1.4
Isocitric acid	1.0
2-Oxoglutaric acid	1.6
Succinic acid	0.8
Fumaric acid	1.1
Malic acid	1.0