Methodology Report

Development of Animal Model for Studying Deep Second-Degree Thermal Burns

Figure 2

Clinical evolution observed in the experimental model of deep second-degree thermal burns in male Wistar rats. (a) Animal’s skin after shaving. (b) Thermal lesion obtained with 10 mm diameter bar, with presence of mild edema. (c) Injured tissue on day 7 after burn induction, presence of thin and dry crust with homogeneous staining and discreet detachment on the edges. (d) Damaged tissue on day 14 after burn induction, presence of granulation tissue in the center of the lesion with a second discreet crust and formation of scar tissue at the edge. (e) Injured tissue on day 21 after the burn induction, discreet presence of granulation tissue with the presence of scar tissue. (f) Injured tissue at day 28 after burn induction, tissue with incomplete healing.
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