Methodology Report

Development of Animal Model for Studying Deep Second-Degree Thermal Burns

Table 1

Clinical parameters evaluated in the experimental model of deep second degree thermal burns in male Wistar rats.

TimeAnimalClinical signs of the experimental model
Edema Hyperemia Crust Scar tissue

7th day1++ *
2+ *
3+ *

14th day1++
2++
3+

21st day1+++
2+++
3+++

28th day1++
2+
3+

The intensity of clinical signs was scored as −: absent; *: present, +: mild, ++: moderate, +++: strong.