Review Article

Artificial Chromosomes to Explore and to Exploit Biosynthetic Capabilities of Actinomycetes

Figure 1

Examples of natural compounds produced by actinomycetes. Vancomycin and daptomycin are synthesized by NRPSs from Amycolatopsis orientalis and Streptomyces roseosporus, respectively; erythromycin, migrastatin, and meridamycin are produced by PKSs in Saccharopolyspora erythraea, Streptomyces platensis, and Streptomyces sp. NRRL 30748.
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