Validation of a New Animal Model of Vulnerable Plaques by Intravascular Optical Coherence Tomography In Vivo

Table 2

Histological findings of plaques from the two experimental groups.

Feature	Group A (𝑛=6)	Group B (𝑛=6)	𝑡	𝑃
Average FCT (𝜇m)	55.01±28.67	141.20±76.57	−2.58	0.0273
Minimum FCT (𝜇m)	48.20±25.08	83.80±39.50	−1.864	0.0920
Average lipid arc (°)	141.67±69.69	263.33±82.62	−2.757	0.0207
CD68 (%)	28.74±14.67	10.69±7.39	2.692	0.0226
SMCs (%)	26.08±12.83	29.52±11.27	−0.493	0.6330
LA (mm^2)	0.898±0.650	0.554±0.284	1.188	0.2624
MP area (mm^2)	1.175±0.421	2.724±1.172	−3.048	0.0213
Min MPT (mm)	0.098 ± 0.031	0.396 ± 0.165	−4.351	0.0063
Average MPT (mm)	0.314 ± 0.069	0.712 ± 0.258	−3.658	0.0115
Max MPT (mm)	0.529 ± 0.137	1.028 ± 0.407	−2.844	0.0288
Average EI	0.804±0.077	0.605±0.134	3.148	0.0104

FCT: fibrous cap thickness; LA: lumen area. MPT: media and plaque thickness; MPA: media and plaque area; EI: eccentric index; SMCs: smooth muscle cells.