The Safety of Cruciferous Plants in Humans: A Systematic Review

Table 1

Eligibility criteria and data extracted¹.

PICOS	Eligibility criteria	Data extracted
Patient	All human subjects were included	Age, concurrent medical conditions and treatments, reason for intervention (where relevant)
Intervention	All types of exposure (oral, topical, or respiratory) to cruciferous plants, their derivatives, or their constituents	Plant or substance exposed to, route of exposure, duration of exposure, dose (if available)
Comparators	Reports with or without a comparator group. Reports without control groups were included in order to include all potential adverse events	Numbers in the intervention and comparator groups (when relevant)
Outcome	Reports of presence or absence of adverse events	Presence or absence of adverse events, description of adverse event, acute management of adverse event (for case reports), outcome (when available), and causality
Study design	All study designs which were relevant to the assessment of safety were included. Studies in all languages were included and translated when necessary	Type of study design and setting

¹PICOS: patient, intervention, comparators, outcome, study design.