Review Article

Posterior Circulation Stroke: Animal Models and Mechanism of Disease

Table 1

Posterior circulation syndromes and associated brain region, clinical signs.

Syndrome(s)Vessel(s)Brain region(s)Contralateral sign(s)Ipsilateral sign(s)

NoneVA, PICACerebellumNoneTruncal, leg, and gait ataxia/dystaxia
Medial medullary, WallenbergASA, VA, PICACaudal MedullaAny sensory input loss hemiplegiaHorner’s syndrome, tongue weakness, dysphagia, hoarseness, loss of facial sensation, nystagmus, vertigo, ataxia
Locked-in, Foville, Millard-Gubler, Marie-foixBA, AICAPonsLoss of pain or temperature sensation, hemiplegiaFacial or lateral gaze weakness, dysarthria, hemiplegia, ataxia
Parinaud, Benedikt, Weber,
Claude
PCAMidbrainTremor, hemiplegia, motor deficit, cerebellar ataxiaParalysis of gaze and accommodation, fixed pupils, CNIII palsy
Dejerine-RoussyPCAThalamusPain syndrome, any sensory input lossNone
Balint, AntonPCAOccipital, Temporal lobesVision loss, blindness denialVision and eye movement loss, misinterpretation of visual objects, blindness denial, loss of visual-motor coordination

VA: vertebral artery; PICA: posterior inferior cerebellar artery; ASA: anterior spinal artery; BA: basilar artery; AICA: anterior inferior cerebellar artery; PCA: posterior cerebral artery; CNIII: cranial nerve three.