Figure 2: A biopsy taken from a lichenoid lesion. Photomicrographs show oral mucosa covered by stratified squamous epithelium which is atrophic and orthokeratinized. (a) The superficial lamina propria contains a dense and a well-demarcated lymphoplasmacytic infiltrate. A perivascular lymphoplasmacytic infiltrate also present in the deeper lamina propria. (b) There is thickening of basement membrane region, loss of well-defined basal cell layer, and frequent keratinocyte apoptosis. Photomicrographs; courtesy of Prof Edward Odell.