Figure 1: This figure depicts the linear HSV-1 strains 17 Syn+ noting specific regions of the genome. The abbreviations are as follows: T R L —terminal repeat long; T R S —terminal repeat short; UL—unique long; US—unique short; I R L —internal repeat long; I R S —internal repeat short. Note that LAT is in two regions of the HSV-1 genome ( T R L and I R L ). An 8.5 kb polyadenylated precursor is transcribed. Within the last domain are two very important immediate-early genes, ICP0 and ICP34.5. Also note the promoter, the CAP site, and a 2.0 kb intron. Further modification results in a 1.5 kb smaller intron.