|
| Mouse name | Use of model | Author, year (reference no.) |
|
| Rag2 (−/−) | Study of ICP0 and ICP34.5 | Halford et al., 1996 [102] |
| Stat1 (−/−) | IFN response to viral infection | Pasieka et al., 2011 [103] |
| INFαβγR (−/−) | IFN response to viral infection | Pasieka et al., 2011[103] |
| IRF-3 (−/−) | Viral induction of type I INF cascade |
Menachery and Leib 2009 [36] |
| Human ApoE 4 (+/+) | ApoE4 role in microglia immune response | Vitek et al., 2009 [104] |
| Stat1 (−/−) | Enhanced pathogenesis of Stat1 deficient mice | Pasieka et al., 2008 [105] |
| Human ApoE3 (+/+) | Human ApoE4 role in ocular herpes pathogenesis | Bhattacharjee et al., 2008 [25] |
| Human ApoE4 (+/+) | Human ApoE4 role in ocular herpes pathogenesis | Bhattacharjee et al., 2008 [25] |
| p19 (−/−) | IL-23 role in the severity of HSV-1 ocular lesions | Kim et al., 2008 [106] |
| ISG15 (−/−) | ISG15 role in host response to viral infection | Lenschow et al., 2007 [107] |
| Stat4 (−/−) | Cytokine involvement in HSV-1 stromal keratitis events | Banerjee et al., 2007 [108] |
| IL-1ra (−/−) | IL-1 role in HSV-1 stromal keratitis | Biswas et al., 2004 [109] |
| scid or rag2 (−/−) | ICP0 role in viral replication | Halford et al., 2006 [110] |
| wt and p53 (−/−) | Role of p43 in HSV-1 replication | Haenchen et al., 2010 [111] |
|
