Figure 3: Mutational profiles of hsa-miR-548-5p (a) and hsa-miR-548-3p (b) populations. Products of hsa-mir-548 gene family are estimated their mutational profiles according to each nucleotide position along miRNA sequence. Although these miRNA sequences have higher sequence similarity, higher level of nucleotide variation can be detected between miR-548-5p and miR-548-3p populations, especially the latter.