Profiling of Age-Related Changes in the Tibialis Anterior Muscle Proteome of the mdx Mouse Model of Dystrophinopathy

Figure 1

Two-dimensional gel electrophoretic analysis of normal mouse tibialis anterior muscle. Shown is a fluorescent RuBPs-stained gel of total extracts from 8 weeks old tibialis anterior muscle. Major protein spots are marked by circles and are numbered 1 to 22. See Table 1 for the mass spectrometric identification of 2D landmark proteins that do not change during aging of the mdx animal model of Duchenne muscular dystrophy. The pH values of the first dimension gel system and molecular mass standards of the second dimension are indicated on the top and on the left of the panels, respectively.