Profiling of Age-Related Changes in the Tibialis Anterior Muscle Proteome of the mdx Mouse Model of Dystrophinopathy

Table 1

List of unchanged landmark 2D protein spots from normal mouse tibialis anterior muscle.

Spot No.	Protein name	Accession No.	Isoelectric point (pI)	Molecular mass (Da)	Number of peptides	Coverage	Mascot score
						(%)
1	Mitochondrial ATP synthase	AAH37127	5.24	56,632	23	64	456
2	Unnamed protein [Mus musculus]	BAC34145	5.75	70,730	12	21	230
3	Pyruvate kinase, isozymes M1/M2	NP_001240812	6.69	58,461	25	51	1149
4	Enolase, beta, isoform 1	NP_031959	6.73	47,337	21	56	450
5	Creatine Kinase, M-type	NP_031736	6.58	43,250	23	47	509
6	Actin, beta	CAA27396	5.78	39,446	12	41	103
7	Tropomyosin, beta chain	NP_033442	4.66	32,931	22	59	395
8	Tropomyosin, beta chain	NP_033442	4.66	32,933	32	15	241
9	Malate dehydrogenase, cytosolic	AAA37423	6.16	36,625	9	36	190
10	Aldolase A, isoform 2	NP_031464	8.31	39,795	24	75	498
11	Glyceraldehyde-3-phosphate dehydrogenase	NP_032110	8.44	36,072	14	57	238
12	Carbonic anhydrase CA3	NP_031632	6.89	29,638	12	43	431
13	Triosephosphate isomerase	AAB48543	5.62	22,720	11	62	248
14	Triosephosphate isomerase	AAB48543	5.62	22,720	11	68	638
15	Troponin TnI, fast skeletal muscle	NP_033431	8.65	21,515	5	20	150
16	Adenylate kinase, isoenzyme 1	NP_067490	5.7	23,330	14	70	184
17	Myosin light chain MLC1/3	NP_067260	4.98	20,697	17	79	426
18	Myosin light chain MLC2	NP_058034	4.82	19,057	15	61	216
19	Myosin light chain MLC2	NP_058034	4.82	19,059	19	81	391
20	Myosin light chain MLC3	AAH59087	4.63	18,968	11	60	222
21	Parvalbumin, alpha	NP_038673	5.02	11,923	12	89	622
22	Myoglobin	NP_038621	7.07	17,116	5	37	98