Research Article
Quantitation of Pyrrole-Imidazole Polyamide in Rat Plasma by High-Performance Liquid Chromatography Coupled with UV Detection
| | Nominal concentration (μg/mL) | Extracted sample in auto sampler (4°C, 24 hrs) | Freezer storage (−20°C, 14 days) | | | RE (%) | RE (%) |
| | HN.49 | QL (1) | 7.8 | 14.0 | | QH (160) | 2.1 | 7.6 | | TGF-1f | QL (0.5) | 1.5 | 6.0 | | QH (160) | −3.0 | 13.2 | | TGF-1t | QL (0.5) | −2.8 | 2.8 | | QH (160) | −0.9 | −1.4 | | HN.50f | QL (2) | −5.4 | −1.8 | | QH (160) | −1.1 | −5.6 | | HN.50t | QL (0.5) | −1.8 | −1.4 | | QH (160) | −1.9 | −1.4 | | LOX-1 | QL (0.5) | −7.5 | 3.2 | | QH (160) | −3.8 | 12.4 |
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