Protection of SH-SY5Y Neuronal Cells from Glutamate-Induced Apoptosis by 3,-Disinapoyl Sucrose, a Bioactive Compound Isolated from Radix Polygala
Effect of DISS against glutamate- (Glu-) induced neurotoxicity in cultured SH-SY5Y cells by flow cytometric DNA analysis. The sub-G1 peaks were determined by flow cytometry. (a) Control, (b) Glu alone, (c) Glu + 0.6 μmol/L DISS, (d) Glu + 6 μmol/L DISS, (e) Glu + 60 μmol/L M DISS. Bar() represents a sub-G1 or hypodiploid DNA fraction.
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